Electrochemical Aspects of Hemosorption

We considered the electrochemical features of hemosorption, based on an electrochemical mechanism of interaction.Activated carbon serves as an electrode, and blood serves as an electrolyte.The proposed electrochemical system revealed a linear correlation between the stationary potential of activated carbon and the platelet count in the carbon/blood system.A "threshold" potential of E = 0.04 V, corresponding to the point of indifference of carbon toward platelets, was obtained.A considerable effect of activated carbon potential on the adsorption of 1,2-dichloroethane and sodium barbital was found.An electrochemical method of premodification of activated carbon, leading to a change of stationary potential by cathodic or anodic treatment in an aqueous solution of sodium chloride, has been developed.A nonfaradaic method of external direct polarization of activated carbon in blood was realized by a special cylindrical column with granular activated carbon.Changes of hematological, morphological, and rheological indexes of blood subsequent to blood perfusion through activated carbon were investigated.The carbon potential was found to be the only determining factor in the interaction between carbon and blood, but the way of polarization of activated carbon had no influence on this interaction.