Key result
Chordal preservation during mitral valve replacement improved 5-year survival compared to conventional valve excision (92% vs. 80%; p=0.001) and preserved left ventricular fractional shortening.
Why the study?
Does chordal preservation improve survival and left ventricular function compared to conventional valve excision in patients undergoing mitral valve replacement?
Population
360 patients undergoing mitral valve replacement for mitral valve disease
Comparison
Total or partial chordal preservation during… vs Conventional valve-excising mitral valve…
Design
Cohort
Follow-up
5 years
Authors
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May support chordal preservation in mitral valve replacement; hypothesis-generating and requires randomized confirmation before practice change.
Cohort (n=360)
Does chordal preservation improve survival and left ventricular function compared to conventional valve excision in patients undergoing mitral valve replacement?
Absolute Event Rate: 92% vs 80%
p-value: p=0.001
Chordal preservation during mitral valve replacement significantly improves 5-year survival and preserves left ventricular function compared to conventional complete valve excision.
Muthialu et al. (2005) conducted a cohort in Mitral valve disease (n=360). Chordopapillary apparatus preservation vs. Valve-excising mitral valve replacement (conventional operation) was evaluated on Survival at 5 years (p=0.001). Chordal preservation during mitral valve replacement improved 5-year survival compared to conventional valve excision (92% vs. 80%; p=0.001) and preserved left ventricular fractional shortening.
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