Key result
Transaortic resection of the obstructing anterior mitral leaflet successfully reduced the left ventricular outflow tract mean gradient from 43 mmHg to 9 mmHg without requiring mitral valve re-replacement.
Why the study?
Left ventricular outflow tract obstruction following mitral valve replacement is a challenging complication.
Population
A 70-year-old female with SAM following leaflet-preserving mitral valve replacement
Design
Case report
Authors
Loading...
May offer valve-sparing relief for late post-MVR LVOT obstruction; hypothesis-generating pending prospective validation.
Case Report (n=1)
Absolute Event Rate: 9% vs 43%
Transaortic resection of the anterior mitral leaflet effectively relieves late-onset severe LVOT obstruction following leaflet-preserving mechanical mitral valve replacement without the need for valve re-replacement.
Nwanna-Nzewunwa et al. (2025) conducted a case report in Left ventricular outflow tract obstruction (LVOTO) after mitral valve replacement (n=1). Transaortic resection of the obstructing anterior mitral leaflet and chordae vs. Pre-operative state was evaluated on Left ventricular outflow tract (LVOT) mean gradient. Transaortic resection of the obstructing anterior mitral leaflet successfully reduced the left ventricular outflow tract mean gradient from 43 mmHg to 9 mmHg without requiring mitral valve re-replacement.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: