Why the study?
Does isradipine improve renal hemodynamics in middle-aged male patients with essential hypertension?
Population
20 middle-aged male patients with essential hypertension
Comparison
Isradipine tablets titrated from 2.5, 5, and 7.5… vs Placebo tablets (crossover design)
Design
RCT, crossover design, double-blind
Follow-up
9 weeks
Authors
Loading...
Supports isradipine for essential hypertension with renal plasma flow gains; confirms RCT benefits on renal hemodynamics.
Does isradipine improve renal hemodynamics in middle-aged male patients with essential hypertension?
Isradipine effectively lowers blood pressure while improving renal plasma flow and maintaining glomerular filtration rate in patients with essential hypertension.
Persson et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: