Key result
Dominant right ventricular pathology in children undergoing bidirectional Glenn shunt was associated with higher early postoperative complications (53% vs 10%) compared to dominant left ventricle.
Why the study?
Patients with univentricular heart account for about 20% of complex heart defects and have the highest mortality, prompting a comparison of BDG outcomes between dominant RV and dominant LV morphologies.
Does dominant right ventricular morphology worsen early outcomes compared to dominant left ventricular morphology in children undergoing bidirectional Glenn shunt?
Observational (n=60)
Yes
Does dominant right ventricular morphology worsen early outcomes compared to dominant left ventricular morphology in children undergoing bidirectional Glenn shunt?
Absolute Event Rate: 53% vs 10%
In children undergoing bidirectional Glenn shunt, dominant right ventricular morphology is associated with significantly worse early outcomes, longer hospital stays, and higher complication rates compared to dominant left ventricular morphology.
May warrant closer monitoring in dominant RV patients; hypothesis-generating for morphology-specific risk stratification.
Background: Patients with UVH currently are accounting for about 20% of patients with complex heart defects, and have the highest mortality. Mortality is high during initial treatment and during long-term follow-up. Aim of the Work: to compare the outcome after BDG procedure in patient with dominant RV and patient with dominant LV as a palliative procedure. Patients and Methods: A prospective comparative non-randomized controlled trial included 60 patient's undergone BDG (30 patients having pathology of dominant RV, and 30 patients having pathology of dominant LV). Patients were collected from Al-Azhar university hospitals and of Misr children hospital during the period from January 2021 and march 2022. Results: during this prospective study we have found significant difference in hospital stay which was about 6days in LV dominant group and 9 days in RV group, and ICU stay was 2 days in LV group and 4 days in RV group. Also early post op. complications were in 3 patients (10%) of LV group and 16 patients (53%) in RV group. Complications after 6 months were in 9 patients (30%) and were all in RV group. Conclusion: Despite improved surgical and medical management, there is a continuous risk of failure after BDG. However in our study there is a significant difference in early out come between the RV dominant and the LV dominant morphology, considering the complications, hospital stay and the ICU stay, which carries a high incidence of comorbidities and more burdens on health care institutions.
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Etreby et al. (2024) conducted an observational in Univentricular heart undergoing bidirectional Glenn shunt (n=60). Dominant right ventricular pathology vs. Dominant left ventricular pathology was evaluated on Early postoperative complications. Dominant right ventricular pathology in children undergoing bidirectional Glenn shunt was associated with higher early postoperative complications (53% vs 10%) compared to dominant left ventricle.
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