Key result
Aortic endoclamping during mitral valve surgery through right minithoracotomy resulted in significantly less fibrillatory arrest compared to external clamping (15% vs 44%; P=0.001).
Why the study?
Does aortic endoclamping reduce fibrillatory arrest or operative times compared to external aortic clamping in patients undergoing mitral valve operation through right minithoracotomy?
Cohort (n=671)
Does aortic endoclamping reduce fibrillatory arrest or operative times compared to external aortic clamping in patients undergoing mitral valve operation through right minithoracotomy?
Absolute Event Rate: 15% vs 44%
p-value: p=0.001
Aortic endoclamping is a safe alternative to external clamping for mitral surgery through right minithoracotomy, reducing the need for fibrillatory arrest without increasing operative times.
Endoclamping was associated with less fibrillatory arrest; leaves open need for randomized trials before practice change.
Objective The effects and benefits of a transaortic endoclamp for mitral valve operation through right minithoracotomy have not been established. Methods The records were examined in 671 patients undergoing mitral valve operation using aortic cannulation through a 6-cm right minithoracotomy in the fourth intercostal space. The ascending aorta was cannulated with a 24-Fr cannula through a 12-mm port in the first intercostal space. The experience from 1998 to 2006 with aortic endoclamping (group A, N = 436) was compared with the experience from 2006 to 2009 with external aortic clamping (group B, N = 235). Aortic endoclamping was achieved with a 30 mL endoclamp introduced through the aortic cannula into the ascending aorta to provide aortic endoclamping, anterograde cardioplegia, and root venting. Percutaneous femoral venous cannulation was used. Results Group A and group B had similar demographics. Endoclamp availability (group A) resulted in significantly less fibrillatory arrest (no clamping) in 67 of 436 (15%) versus 104 of 235 (44%) patients in group B (P = 0.001). In patients with aortic clamping, endoclamp (group A) versus external clamp (group B) was not a determinant of clamp time or pump time. Hospital and late outcomes were not different between groups. No patient complications could be attributed to the endoclamp. Conclusions Aortic endoclamping requires no more clamp or pump time than external clamping and can provide a more bloodless field than ventricular fibrillation without obstructing hardware. Aortic endoclamping is a safe alternative for mitral surgery through right minithoracotomy.
No takes yet. Share an insight, caveat, or question.
Glower et al. (2010) conducted a cohort in Mitral valve disease requiring surgery (n=671). Aortic endoclamping vs. External aortic clamping was evaluated on Fibrillatory arrest (no clamping) (p=0.001). Aortic endoclamping during mitral valve surgery through right minithoracotomy resulted in significantly less fibrillatory arrest compared to external clamping (15% vs 44%; P=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: