Key result
Aortic endoclamping during mitral valve surgery through right minithoracotomy resulted in significantly less fibrillatory arrest compared to external clamping (15% vs 44%, P=0.001).
Why the study?
Does aortic endoclamping reduce fibrillatory arrest and operative times compared to external aortic clamping in patients undergoing mitral valve operation through right minithoracotomy?
Cohort (n=671)
Does aortic endoclamping reduce fibrillatory arrest and operative times compared to external aortic clamping in patients undergoing mitral valve operation through right minithoracotomy?
Absolute Event Rate: 15% vs 44%
p-value: p=0.001
Aortic endoclamping is a safe alternative to external clamping for mitral valve surgery through right minithoracotomy, reducing the need for fibrillatory arrest without increasing operative times.
Endoclamping was associated with less fibrillatory arrest; supports alternative use but leaves open randomized confirmation.
OBJECTIVE: : The effects and benefits of a transaortic endoclamp for mitral valve operation through right minithoracotomy have not been established. METHODS: : The records were examined in 671 patients undergoing mitral valve operation using aortic cannulation through a 6-cm right minithoracotomy in the fourth intercostal space. The ascending aorta was cannulated with a 24-Fr cannula through a 12-mm port in the first intercostal space. The experience from 1998 to 2006 with aortic endoclamping (group A, N = 436) was compared with the experience from 2006 to 2009 with external aortic clamping (group B, N = 235). Aortic endoclamping was achieved with a 30 mL endoclamp introduced through the aortic cannula into the ascending aorta to provide aortic endoclamping, anterograde cardioplegia, and root venting. Percutaneous femoral venous cannulation was used. RESULTS: : Group A and group B had similar demographics. Endoclamp availability (group A) resulted in significantly less fibrillatory arrest (no clamping) in 67 of 436 (15%) versus 104 of 235 (44%) patients in group B (P = 0.001). In patients with aortic clamping, endoclamp (group A) versus external clamp (group B) was not a determinant of clamp time or pump time. Hospital and late outcomes were not different between groups. No patient complications could be attributed to the endoclamp. CONCLUSIONS: : Aortic endoclamping requires no more clamp or pump time than external clamping and can provide a more bloodless field than ventricular fibrillation without obstructing hardware. Aortic endoclamping is a safe alternative for mitral surgery through right minithoracotomy.
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Glower et al. (2010) conducted a cohort in Mitral valve operation (n=671). Aortic endoclamping vs. External aortic clamping was evaluated on Fibrillatory arrest (no clamping) (p=0.001). Aortic endoclamping during mitral valve surgery through right minithoracotomy resulted in significantly less fibrillatory arrest compared to external clamping (15% vs 44%, P=0.001).
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