Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery

This is the authors' abstract. We don't add key points for this paper.

OBJECTIVE: To investigate the influence of patient's age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE). METHOD: A retrospective observational investigation performed from a cohort of patients from 2000 to 2012. RESULTS: A total of 229 patients were included. One-hundred and eleven of 179 patients (62%) were classified as Engel I in the group with < 50 years old, whereas 33 of 50 (66%) in the group with ≥ 50 years old group (p = 0.82). From those Engel I, 88 (61%) reported epilepsy duration inferior to 10 years and 56 (39%) superior to 10 years (p < 0.01). From the total of patients not seizure free, 36 (42%) reported epilepsy duration inferior to 10 years and 49 (58%) superior to 10 years (p < 0.01). CONCLUSION: Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.