Key result
Multiple valve surgery for native valve infective endocarditis was not associated with a significant difference in late mortality compared to single valve surgery (OR 0.909).
Why the study?
Does multiple valve surgery compared to single valve surgery affect mortality and morbidity in patients with native valve infective endocarditis?
Cohort (n=90)
No
Does multiple valve surgery compared to single valve surgery affect mortality and morbidity in patients with native valve infective endocarditis?
In patients with native valve infective endocarditis, multiple valve surgery is not an independent predictor of worse perioperative or long-term mortality and morbidity compared to single valve surgery.
No excess late mortality risk with multiple valve surgery in native valve IE; leaves open need for prospective data on morbidity and generalizability.
BACKGROUND: Surgical treatment of infective endocarditis (IE) remains a challenge, especially in cases of multiple valve surgery. We evaluated the clinical outcomes of native valve IE and compared the outcomes of single valve surgery with those of multiple valve surgery. MATERIALS AND METHODS: From 1997 to 2011, 90 patients underwent surgery for native valve IE; 67 patients with single valve surgery (single valve group) and 23 patients with multiple valve surgery (multiple valve group). The mean follow-up duration was 73.1±47.4 months. RESULTS: The surgical mortality in the total cohort was 4.4%. The overall survival (p=0.913) and valve-related event-free survival (p=0.204) did not differ between the two groups. The independent predictor of postoperative complications was New York Heart Association class (p=0.001). Multiple valve surgery was not a significant predictor of surgical mortality (p=0.225) or late mortality (p=0.936). Uncontrolled infection, urgent or emergency surgery, and postoperative complications were identified as independent predictors of valve-related morbidity, excluding multiple valve surgery (p=0.072). CONCLUSION: In native valve IE, multiple valve surgery as a factor was not an independent predictor of mortality and morbidity. The number of surgically corrected valves in native IE seems to be unrelated to perioperative and long-term outcomes.
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Kim et al. (2013) conducted a cohort in Native valve infective endocarditis (n=90). Multiple valve surgery vs. Single valve surgery was evaluated on Late mortality (OR 0.909, 95% CI 0.090-9.207, p=0.936). Multiple valve surgery for native valve infective endocarditis was not associated with a significant difference in late mortality compared to single valve surgery (OR 0.909).
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