Key result
Surgical treatment for native valve endocarditis resulted in an in-hospital mortality of 13.8% and a 5-year survival rate of 77.2%, with ESRD and urgent surgery as independent risk factors.
Why the study?
This study evaluated the short- and long-term results of surgical treatment for native valve endocarditis and investigated risk factors associated with mortality.
Cohort (n=29)
No
Surgical treatment for native valve endocarditis has a 5-year survival rate of 77.2%, but carries significant in-hospital mortality risk, particularly for patients with ESRD or those requiring urgent surgery.
BACKGROUND: The aim of this study was to evaluate the short-term and long-term results of surgical treatment for native valve endocarditis (NVE) and to investigate the risk factors associated with mortality. METHODS: Data including patients' characteristics, operative findings, postoperative results, and survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital. RESULTS: A total of 29 patients underwent surgery for NVE (affecting the mitral valve in 20 patients and the aortic valve in 9) between 2003 and 2017. During the follow-up period (median, 46.9 months; interquartile range, 19.1-107.0 months), the 5-year survival rate was 77.2%. In logistic regression analysis, body mass index (p=0.031; odds ratio [OR], 0.574; 95% confidence interval [CI], 0.346-0.951), end-stage renal disease (ESRD) (p=0.026; OR, 24.0; 95% CI, 1.459-394.8), and urgent surgery (p=0.010; OR, 34.5; 95% CI, 2.353-505.7) were significantly associated with in-hospital mortality. Based on Cox proportional hazard regression analysis, the statistically significant predictors of long-term outcomes were hypertension, ESRD, and urgent surgery. CONCLUSION: Surgical treatment for NVE is associated with considerable mortality. The in-hospital mortality and 5-year survival rates of this study were 13.8% and 77.2%, respectively. Underlying conditions, including hypertension and ESRD, and urgent surgery were independent risk factors for unfavorable outcomes.
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Park et al. (2020) conducted a cohort in Native valve endocarditis (n=29). Surgical treatment was evaluated on In-hospital mortality. Surgical treatment for native valve endocarditis resulted in an in-hospital mortality of 13.8% and a 5-year survival rate of 77.2%, with ESRD and urgent surgery as independent risk factors.
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