Key result
Aortic PVE surgery is linked to ~4-fold higher early mortality compared to native valve endocarditis.
Why the study?
Clinical predictors and outcomes of surgical treatment for active infective endocarditis involving native and prosthetic valves were not well defined.
Population
45 patients with active infective endocarditis (30 NVE, 15 PVE) treated surgically between 1971 and 1991
Comparison
Native valve endocarditis vs prosthetic valve endocarditis
Design
Observational cohort study
Authors
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Higher early mortality after surgery for prosthetic versus native aortic valve endocarditis warrants caution in case selection; this cohort study leaves open optimal timing and confounders.
Observational (n=45)
Absolute Event Rate: 36% vs 8%
Early surgical intervention for active infective endocarditis is recommended despite the risk of cardiac failure, though early mortality is significantly higher in patients with prosthetic valve involvement and severe heart failure.
Abe et al. (1993) conducted an observational in Active infective endocarditis (n=45). Surgical treatment was evaluated on Early mortality. Surgical treatment of active infective endocarditis resulted in significantly higher early mortality for aortic prosthetic valve endocarditis (36%) than aortic native valve endocarditis (8%).
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