Key result
The hemi-Commando procedure for invasive double-valve infective endocarditis resulted in an 8% hospital mortality rate, with 91% 1-year survival and 82% 3-year survival.
Why the study?
Does the hemi-Commando procedure provide acceptable early and mid-term outcomes in patients with invasive double-valve infective endocarditis involving the intervalvular fibrosa?
Cohort (n=37)
Does the hemi-Commando procedure provide acceptable early and mid-term outcomes in patients with invasive double-valve infective endocarditis involving the intervalvular fibrosa?
The hemi-Commando procedure is a feasible treatment option for intervalvular fibrosa reconstruction in high-risk patients with invasive double-valve infective endocarditis, enabling preservation of the mitral valve with acceptable early and mid-term survival.
Supports hemi-Commando feasibility in selected invasive double-valve IE; leaves open need for comparative trials.
OBJECTIVES: Surgical management of invasive double-valve infective endocarditis (IE) involving the intervalvular fibrosa (IVF) is a technical challenge that requires extensive debridement followed by complex reconstruction. In this study, we present the early and mid-term outcomes of the hemi-Commando procedure and aortic root replacement with reconstruction of IVF using an aortomitral allograft. METHODS: From 2010 to 2017, 37 patients with IE involving the IVF underwent the hemi-Commando procedure. Postoperative clinical data and echocardiograms were reviewed for the assessment of cardiac structural integrity and clinical outcomes. RESULTS: Twenty-nine (78%) cases were redo surgery and 15 (41%) were emergency surgery. Preoperatively, 70% (n = 26) of patients were admitted to the intensive care unit and 11% (n = 4) of patients were in septic shock. Ten (27%) patients had native aortic valve IE, while 27 (73%) patients had prosthetic valve IE. Hospital death occurred in 8% (n = 3) of patients due to multisystem organ failure. Postoperative echocardiogram showed no aortic regurgitation in 86% (n = 32) and mild regurgitation in 14% (n = 5) of patients, while mitral regurgitation prevalence was none/trivial in 62% (n = 23), mild in 32% (n = 12) and moderate in 5%. Intact IVF reconstruction was confirmed in all patients with no abnormal communication between the left heart chambers. One-year survival was 91%, while 3-year survival was 82%. Mid-term follow up revealed 1 death secondary to recurrent IE. CONCLUSIONS: Compared to double-valve replacement with IVF reconstruction ('Commando operation'), the early and mid-term outcomes of the hemi-Commando procedure proved to be a feasible treatment option for IVF reconstruction, enabling preservation of the mitral valve and the subvalvular apparatus in high-risk patients with invasive double-valve IE.
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Elgharably et al. (2017) conducted a cohort in Invasive double-valve infective endocarditis involving the intervalvular fibrosa (n=37). Hemi-Commando procedure and aortic root replacement with reconstruction of IVF using an aortomitral allograft was evaluated on Hospital death. The hemi-Commando procedure for invasive double-valve infective endocarditis resulted in an 8% hospital mortality rate, with 91% 1-year survival and 82% 3-year survival.
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