Key result
Rhinoviremia occurred in 11.4% of children with RV-positive respiratory infections and was significantly more common during asthma exacerbations compared to other diseases (25% vs 5%, p=0.01).
Why the study?
Does rhinovirus viremia occur in children with respiratory infections and is it associated with specific clinical characteristics?
Population
119 children with respiratory infections
Comparison
Detection of rhinovirus in blood by semi-nested… vs Rhinovirus-negative control subjects
Design
Cross-sectional
Authors
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Rhinoviremia was associated with asthma exacerbations; leaves open its causal role and any change to pediatric testing or management.
Cross-Sectional (n=221)
Does rhinovirus viremia occur in children with respiratory infections and is it associated with specific clinical characteristics?
Absolute Event Rate: 25% vs 5%
p-value: p=0.01
Rhinovirus viremia can occur in normal children during respiratory infections and is particularly common early in acute asthma exacerbations.
Xatzipsalti et al. (2005) conducted a cross-sectional in Respiratory infections (n=221). Asthma exacerbation vs. Other respiratory diseases was evaluated on Presence of rhinovirus in the blood (rhinoviremia) (p=0.01). Rhinoviremia occurred in 11.4% of children with RV-positive respiratory infections and was significantly more common during asthma exacerbations compared to other diseases (25% vs 5%, p=0.01).
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