Why the study?
Does determination of free IGF-I serum concentration predict the outcome of a GH provocative test in adults suspected of GHD?
Population
1430 healthy children, adolescents, and adults, and 108 adult patients previously treated with GH in…
Design
Cross-sectional
Authors
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Free IGF-I lacks diagnostic superiority for suspected adult GHD; leaves open incremental value beyond total IGF-I or IGFBP-3 in prospective studies.
Does determination of free IGF-I serum concentration predict the outcome of a GH provocative test in adults suspected of GHD?
Free IGF-I serum levels can predict the outcome of a GH provocative test in adults suspected of GHD, but offer no significant advantage over total IGF-I or IGFBP-3.
Juul et al. (1997) studied this question.
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