Key result
Percutaneous implantation of a newly designed valved stent in the aortic position was successfully performed in a lamb model, maintaining perfect valve function without obstructing the coronary arteries at 4 weeks.
Population
Animal model for percutaneous aortic valve replacement
Design
Preclinical
Authors
Loading...
Supports progression to larger preclinical studies; leaves open translation to human transcatheter aortic valve replacement.
A newly designed stent and deployment strategy using a bovine jugular vein segment demonstrates initial feasibility for percutaneous aortic valve replacement in an animal model.
Younès Boudjemline (2001) conducted a letter in Aortic valve disease (animal model). Percutaneous valved stent implantation was evaluated on Valve function and coronary artery patency. Percutaneous implantation of a newly designed valved stent in the aortic position was successfully performed in a lamb model, maintaining perfect valve function without obstructing the coronary arteries at 4 weeks.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: