Key result
Pulse pressure variability during mechanical thrombectomy was independently associated with worse 3-month functional outcome (adjusted OR 1.40; 95% CI 1.09-1.79; P=0.008).
Why the study?
Does pulse pressure variability during mechanical thrombectomy predict worse functional outcomes in acute ischemic stroke patients?
Population
343 acute ischemic stroke patients presenting with large vessel occlusion undergoing mechanical thrombectomy
Design
Cohort
Follow-up
3 months
Authors
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May signal need for hemodynamic stability in thrombectomy; hypothesis-generating and should not yet change practice.
Cohort (n=343)
Does pulse pressure variability during mechanical thrombectomy predict worse functional outcomes in acute ischemic stroke patients?
Odds Ratio: 1.4 (95% CI 1.09–1.79)
p-value: p=0.008
Increased pulse pressure variability during mechanical thrombectomy independently predicts worse 3-month functional outcomes in acute ischemic stroke patients.
Maïer et al. (2018) conducted a cohort in Acute ischemic stroke with large vessel occlusion (n=343). Pulse pressure variability was evaluated on Worse functional outcome at 3 months (modified Rankin Scale) (adjusted OR 1.40, 95% CI 1.09-1.79, p=0.008). Pulse pressure variability during mechanical thrombectomy was independently associated with worse 3-month functional outcome (adjusted OR 1.40; 95% CI 1.09-1.79; P=0.008).
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