Key result
Having three or more cardiac surgeries was associated with a significantly lower median health-related quality of life score compared to the overall CHD cohort (81 vs 95; p<0.001).
Why the study?
Does the number of cardiac surgeries affect health-related quality of life in children with congenital heart disease?
Observational (n=337)
Yes
Does the number of cardiac surgeries affect health-related quality of life in children with congenital heart disease?
Answers are grounded in this paper and cite their sources.
Children with congenital heart disease who require three or more cardiac surgeries or have a univentricular heart experience significantly lower health-related quality of life and cognitive ability.
BACKGROUND: As survival of children with CHD needing surgery has improved significantly, the need for follow-up in terms of health-related quality of life has become increasingly important. In this study, we sought to describe health-related quality of life in children with CHD in relation to cardiac surgery. METHODS: A retrospective Swedish National Registry for Congenital Heart Disease survey measured using DISABKIDS chronic generic measure-short version included 337 children (age 9-17 years; 39% girls). The majority (n=319, 95%) of children had a biventricular heart, whereas the remaining had a univentricular heart. Cardiac surgery was performed in 197 (58%) children. Health-related quality of life was expressed as total score (100 highest) and given as medians and 10-90th percentiles. RESULTS: The overall total score was 95 (88-100). Children with a biventricular heart who had undergone three or more surgeries (n=31; 9%) had the lowest total score of 81 (61-97; p<0.001). Children with two or more surgeries and those with univentricular heart were classified in NYHA II more frequently than children with one or no cardiac surgery (p=0.005 and <0.001, respectively). Children with three or more surgeries and those with univentricular heart needed more help at school (p<0.001). Compared with children with other chronic diseases, children with CHD had a high total score except for children with three or more surgeries who had comparable total scores with children with other chronic diseases. CONCLUSION: Children with three or more cardiac surgeries and those with a univentricular heart appear to have lower health-related quality of life, cognitive ability, and NYHA classification.
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Svensson et al. (2016) conducted an observational in Congenital Heart Disease (n=337). Three or more cardiac surgeries vs. Fewer than three cardiac surgeries / overall cohort was evaluated on Health-related quality of life (DISABKIDS total score) (p=<0.001). Having three or more cardiac surgeries was associated with a significantly lower median health-related quality of life score compared to the overall CHD cohort (81 vs 95; p<0.001).
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