Key result
A single base pair change (G to C) in the feline MYBPC3 gene was identified in affected cats, resulting in a reduction in the protein in myocardium compared to controls (P<0.001).
Authors
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May aid feline cardiomyopathy models; leaves open relevance to human MYBPC3 disease.
p-value: p=<0.001
Meurs et al. (2005) studied Familial hypertrophic cardiomyopathy (HCM). MYBPC3 gene mutation (G to C) vs. Control cats was evaluated on Reduction in MYBPC3 protein in myocardium (p=<0.001). A single base pair change (G to C) in the feline MYBPC3 gene was identified in affected cats, resulting in a reduction in the protein in myocardium compared to controls (P<0.001).
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