Why the study?
Does lower body negative pressure affect hand blood flow?
Does lower body negative pressure affect hand blood flow?
Lower body negative pressure induces a dose-dependent reduction in hand blood flow, with greater negative pressures causing sustained reductions unlike typical orthostatic reflexes.
Threshold effects in LBNP vasoconstriction warrant cautious interpretation; leaves open validation in orthostatic syndromes.
Exposure to mild degrees of lower body negative pressure (between atmospheric and 40 mm Hg below atmospheric) caused a transient reduction in hand blood flow. Greater reductions in lower body negative pressure (40 mm Hg or more below atmospheric) led to a more sustained reduction in hand blood flow. This sustained response to LBNP is unlike the reflex effects on hand blood flow caused by tilting into the foot-down position. The possibility that the response is the result of several different stimuli is discussed.
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McNamara et al. (1969) studied this question.
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