Key result
Noninvasive surveillance techniques for cardiac allograft rejection currently have poor specificity, meaning invasive endomyocardial biopsy remains the gold standard.
Why the study?
Can noninvasive surveillance techniques safely and accurately replace endomyocardial biopsy for detecting cardiac allograft rejection?
Can noninvasive surveillance techniques safely and accurately replace endomyocardial biopsy for detecting cardiac allograft rejection?
Endomyocardial biopsy remains the gold standard for cardiac allograft rejection surveillance due to the poor specificity of current noninvasive techniques.
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Noninvasive methods cannot yet replace biopsy; leaves open need for higher-specificity alternatives in transplant surveillance.
Mehra et al. (2002) conducted a review in Cardiac allograft rejection. Noninvasive monitoring techniques vs. Invasive endomyocardial biopsy was evaluated. Noninvasive surveillance techniques for cardiac allograft rejection currently have poor specificity, meaning invasive endomyocardial biopsy remains the gold standard.
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