Key result
Under acute hypoxia, the non-invasive estimation of lactate threshold using VE/VO2 (1.37 l/min) significantly underestimated the actual blood lactate threshold (1.67 l/min, P=0.0001), resulting in a pseudo-threshold.
Why the study?
Does acute hypoxia alter the accuracy of non-invasive lactate threshold estimation from ventilatory gas exchange indices in healthy males?
Population
7 sedentary healthy males, mean age 21.4±1.2 years
Comparison
Incremental exercise test breathing 12% O2 vs Incremental exercise test breathing room air
Design
Other, Plots were randomly number-coded for the determination of lactate…
Authors
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Clinicians should interpret VE/VO2 thresholds cautiously in acute hypoxia; leaves open whether ventilatory indices need hypoxia-specific calibration.
Does acute hypoxia alter the accuracy of non-invasive lactate threshold estimation from ventilatory gas exchange indices in healthy males?
Absolute Event Rate: 1.37% vs 1.67%
p-value: p=0.0001
Acute hypoxia induces a pseudo-threshold behavior in ventilatory gas exchange indices, leading to an underestimation of the true lactate threshold during incremental exercise.
Özçelik et al. (2006) studied Healthy (n=7). Acute hypoxia (12% O2) vs. Normoxia (room air) was evaluated on Lactate threshold estimation (VE/VO2 vs blood lactate) under hypoxia (p=0.0001). Under acute hypoxia, the non-invasive estimation of lactate threshold using VE/VO2 (1.37 l/min) significantly underestimated the actual blood lactate threshold (1.67 l/min, P=0.0001), resulting in a pseudo-threshold.
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