Key result
Hypoxia reduces peak VO2 by ~13% versus normoxia during incremental exercise to exhaustion.
Population
9 healthy young men
Comparison
Incremental exercise to exhaustion in hypoxia vs Incremental exercise to exhaustion in normoxia
Design
Other
Authors
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Hypoxia lowers peak VO2 in healthy men; leaves open whether lactate-catecholamine coupling or threshold discordance applies to clinical populations.
Absolute Event Rate: 3635% vs 4164%
p-value: p=<0.05
The tight coupling between blood lactate and plasma catecholamines during incremental exercise persists in hypoxia, suggesting a common mechanism or causative link.
Hughson et al. (1995) studied Healthy (n=9). Hypoxia vs. Normoxia was evaluated on Peak VO2 (p=<0.05). Hypoxia significantly reduced peak VO2 compared to normoxia (3,635 vs 4,164 ml/min; P<0.05) during incremental exercise to exhaustion in healthy young men.
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