Key result
A 10-week combined training program decreased serum concentrations of the proinflammatory cytokine interleukin-18 and increased the anti-inflammatory cytokine interleukin-10, while reducing metabolic risk factors in elderly women with non-alcoholic fatty liver disease.
Why the study?
Non-alcoholic fatty liver disease is strongly associated with altered inflammatory cytokine levels and metabolic abnormalities, prompting investigation into the effects of combined exercise training in elderly women with NAFLD.
Does combined training improve inflammatory cytokines and metabolic factors in elderly women with non-alcoholic fatty liver disease?
RCT (n=24)
Randomly divided
No
Does combined training improve inflammatory cytokines and metabolic factors in elderly women with non-alcoholic fatty liver disease?
Combined training for 10 weeks significantly improves metabolic parameters and reduces liver fat in elderly women with non-alcoholic fatty liver disease.
Answers are grounded in this paper and cite their sources.
Combined exercise may shift inflammatory balance in elderly women with NAFLD; leaves open effects on hard outcomes in larger trials.
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Norouzpour et al. (2022) conducted an RCT in Non-alcoholic fatty liver disease (NAFLD) (n=24). Combined training (aerobic and resistance) vs. Control (no exercise) was evaluated on Serum concentration of interleukin 18 (IL-18) (p=0.00). A 10-week combined training program decreased serum concentrations of the proinflammatory cytokine interleukin-18 and increased the anti-inflammatory cytokine interleukin-10, while reducing metabolic risk factors in elderly women with non-alcoholic fatty liver disease.
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