Key result
Late arterial switch operation (≥3 weeks) for TGA-IVS had similar in-hospital mortality (3.8% vs 5.5%) compared to early switch, but significantly prolonged postoperative stay (18.9 vs 12.5 days).
Why the study?
Does a late primary arterial switch operation (≥3 weeks) compared to an early operation (<3 weeks) affect in-hospital mortality and postoperative recovery in patients with TGA-IVS?
Cohort (n=380)
Does a late primary arterial switch operation (≥3 weeks) compared to an early operation (<3 weeks) affect in-hospital mortality and postoperative recovery in patients with TGA-IVS?
Absolute Event Rate: 3.8% vs 5.5%
The primary arterial switch operation can be feasibly extended beyond 3 weeks of age in patients with TGA-IVS without increasing in-hospital mortality, though it prolongs postoperative recovery.
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Supports feasibility of delayed switch in TGA-IVS without mortality increase; leaves open recovery trade-offs pending prospective trials.
Kang et al. (2004) conducted a cohort in Transposition of the great arteries and intact ventricular septum (TGA-IVS) (n=380). Late arterial switch operation (≥3 weeks) vs. Early arterial switch operation (<3 weeks) was evaluated on In-hospital mortality. Late arterial switch operation (≥3 weeks) for TGA-IVS had similar in-hospital mortality (3.8% vs 5.5%) compared to early switch, but significantly prolonged postoperative stay (18.9 vs 12.5 days).
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