Key result
Transcatheter closure using Amplatzer VSD occluders achieved total occlusion in 95% of muscular and 92.3% of perimembranous VSDs, with a 7.6% embolization rate in perimembranous cases.
Why the study?
Does transcatheter closure using Amplatzer VSD occluders achieve total occlusion in patients with muscular and perimembranous VSDs?
Observational (n=35)
Does transcatheter closure using Amplatzer VSD occluders achieve total occlusion in patients with muscular and perimembranous VSDs?
Transcatheter closure of muscular and perimembranous VSDs using Amplatzer occluders achieves high occlusion rates and appears to be a safe alternative to surgery.
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May support transcatheter VSD closure in select cases; leaves open need for RCTs versus surgery.
Thanopoulos et al. (2003) conducted an observational in muscular and perimembranous ventricular septal defects (n=35). Amplatzer VSD occluders was evaluated on Overall total occlusion. Transcatheter closure using Amplatzer VSD occluders achieved total occlusion in 95% of muscular and 92.3% of perimembranous VSDs, with a 7.6% embolization rate in perimembranous cases.
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