Key result
Among cases of juvenile sudden cardiovascular death, 24% had severe coronary atherosclerosis, which was clinically silent prior to death in 68% of these individuals.
Observational (n=84)
Coronary atherosclerosis can be completely silent in young people, with sudden death as its first clinical manifestation, often occurring at rest and associated with single-vessel disease without acute thrombosis.
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Sudden death may be first sign of silent juvenile atherosclerosis; case reports leave open value of targeted screening.
Corrado et al. (1988) conducted an observational in Juvenile sudden death (n=84). Coronary atherosclerosis was evaluated on Presence of ≥70% atherosclerotic coronary stenosis among cardiovascular sudden deaths. Among cases of juvenile sudden cardiovascular death, 24% had severe coronary atherosclerosis, which was clinically silent prior to death in 68% of these individuals.
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