Key result
Fibromuscular dysplasia of the artery supplying the cardiac conduction system was identified as the sole pathologic change in two young individuals who experienced sudden death.
Case Report (n=2)
Fibromuscular dysplasia of the small coronary arteries supplying the conduction system can be a rare cause of sudden death in young, apparently healthy individuals.
May prompt targeted conduction artery histology in young sudden death autopsies; hypothesis-generating and leaves prevalence undetermined.
Two cases of sudden death of young people in apparently good health are reported. The only pathologic change found was a fibromuscular dysplasia of the artery supplying the conduction system of the heart with an important narrowing of the lumen and strong thickening of the arterial wall. The first case was of a 12-year-old girl who died suddenly while skiing; the second was of a 32-year-old man who died while talking to his wife. No other pathologic changes were found at autopsy, and the results of toxicologic analysis were negative. There was no individual or family history of cardiac diseases. These cases illustrate the importance of an analysis of the conduction system, including examination of the intramural coronary arteries supplying the conduction system.
No takes yet. Share an insight, caveat, or question.
Michaud et al. (2001) conducted a case report in Sudden death (n=2). Fibromuscular dysplasia of the artery supplying the conduction system was evaluated on Sudden death. Fibromuscular dysplasia of the artery supplying the cardiac conduction system was identified as the sole pathologic change in two young individuals who experienced sudden death.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: