Key result
Mid- and basal peak systolic longitudinal strain at rest effectively detected severe left main or three-vessel coronary artery disease (AUC 0.83; 95% CI 0.75-0.91).
Why the study?
Does peak systolic longitudinal strain at rest predict the presence of severe coronary artery disease in patients without regional wall motion abnormalities?
Population
108 patients without regional wall motion abnormality at resting echocardiogram who underwent…
Comparison
Peak systolic longitudinal strain measurement… vs Coronary angiography (reference standard)
Design
Cross-sectional
Authors
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May support resting strain to flag severe multivessel CAD without wall motion abnormalities; leaves open prospective validation before clinical adoption.
Cross-Sectional (n=108)
Does peak systolic longitudinal strain at rest predict the presence of severe coronary artery disease in patients without regional wall motion abnormalities?
Effect estimate: AUC 0.83 (95% CI 0.75-0.91)
Resting 2D peak systolic longitudinal strain can help identify severe coronary artery disease in patients who do not exhibit regional wall motion abnormalities.
Choi et al. (2009) conducted a cross-sectional in Coronary artery disease (n=108). Peak systolic longitudinal strain (PSLS) at rest vs. Patients with one- or two-vessel CAD or without CAD was evaluated on Detection of severe CAD (left main or three-vessel CAD) (AUC 0.83, 95% CI 0.75-0.91). Mid- and basal peak systolic longitudinal strain at rest effectively detected severe left main or three-vessel coronary artery disease (AUC 0.83; 95% CI 0.75-0.91).
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