Key result
ROX coupler implantation led to similar reductions in office systolic blood pressure in patients with combined (-29 mm Hg) versus isolated systolic hypertension (-22 mm Hg; P=0.445).
Why the study?
Does the creation of an arteriovenous anastomosis using the ROX coupler reduce blood pressure similarly in patients with combined hypertension versus isolated systolic hypertension?
Population
42 patients with true treatment-resistant hypertension, stratified into combined hypertension and isolated…
Comparison
Creation of an arteriovenous anastomosis using… vs Patients with combined hypertension compared to…
Design
Cohort
Follow-up
6 months
Authors
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May support ROX coupler across resistant hypertension phenotypes; leaves open need for randomized confirmation.
RCT (n=42)
Randomized
Does the creation of an arteriovenous anastomosis using the ROX coupler reduce blood pressure similarly in patients with combined hypertension versus isolated systolic hypertension?
Absolute Event Rate: -29% vs -22%
p-value: p=0.445
Creation of an arteriovenous anastomosis using the ROX coupler effectively lowers blood pressure in treatment-resistant hypertension regardless of whether the patient has combined or isolated systolic hypertension.
Ott et al. (2016) conducted an RCT in Treatment-resistant hypertension (n=42). ROX coupler implantation (Combined Hypertension) vs. ROX coupler implantation (Isolated Systolic Hypertension) was evaluated on Reduction in office systolic BP (p=0.445). ROX coupler implantation led to similar reductions in office systolic blood pressure in patients with combined (-29 mm Hg) versus isolated systolic hypertension (-22 mm Hg; P=0.445).
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