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No immediate clinical implications; extends SR membrane specializations from skeletal to mammalian cardiac muscle.
Freeze-fracture studies of papillary muscles from cat, rabbit and dog reveal the presence of a fenestrated collar of the sarcoplasmic reticulum (SR) in the region of the M band. This membrane specialization is structurally similar to that observed previously in skeletal muscle. This report includes mammalian cardiac muscle on the list of those muscles containing this SR membrane structure.
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W B Van Winkle (1977) studied this question.
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