Key result
Intraoperative hypotension significantly increased the risk of postoperative cognitive dysfunction (OR 5.512) in elderly patients 7 days after surgery for oral malignancies.
Why the study?
The study aimed to analyse the incidence and risk factors for postoperative cognitive dysfunction in elderly adults undergoing surgery for oral malignancies.
Population
112 elderly patients (aged ≥ 55 years) undergoing surgery for oral malignancies
Comparison
Patients who developed POCD vs those who did not (non-POCD)
Design
Single-center observational cohort study
Follow-up
7 days after surgery
Authors
Loading...
Alerts to POCD risk in elderly oral malignancy surgery; leaves open prospective validation of risk factors.
Observational (n=112)
No
Odds Ratio: 5.512 (95% CI 1.24–24.506)
p-value: p=0.025
Intraoperative hypotension, hypertension, and prolonged anesthesia are among the independent risk factors for postoperative cognitive dysfunction in elderly patients undergoing surgery for oral malignancies.
Wu et al. (2023) conducted an observational in Oral malignancies (n=112). Intraoperative hypotension vs. No intraoperative hypotension was evaluated on Postoperative cognitive dysfunction (POCD) at 7 days (OR 5.512, 95% CI 1.240-24.506, p=0.025). Intraoperative hypotension significantly increased the risk of postoperative cognitive dysfunction (OR 5.512) in elderly patients 7 days after surgery for oral malignancies.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: