Why the study?
Does theophylline compared to enprofylline alter coronary sinus blood flow and cardiac oxygen extraction in healthy subjects?
Does theophylline compared to enprofylline alter coronary sinus blood flow and cardiac oxygen extraction in healthy subjects?
Theophylline, but not enprofylline, increases coronary vascular resistance, indicating a physiological role for endogenous adenosine in regulating coronary blood flow in humans.
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Theophylline may reduce coronary perfusion in patients; confirms endogenous adenosine regulates human coronary blood flow.
Edlund et al. (1995) studied this question.
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