Key result
A method using 18 radiopaque markers and biplane cineradiography successfully measured in vivo canine right ventricular volume at 60 Hz, demonstrating RV ejection without significant isovolumic contraction.
Population
6 dogs (17-22 kg) under pentobarbital anesthesia
Design
Preclinical
Authors
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Advances canine RV volume assessment; leaves open translation to human right heart studies.
A novel method using radiopaque markers and biplane cineradiography enables rapid, high-frequency in vivo determination of instantaneous right ventricular pressure and volume in a canine model.
Schwiep et al. (1988) studied this question. Radiopaque marker implantation and biplane cineradiography was evaluated on Right ventricular volume and pressure-volume loops. A method using 18 radiopaque markers and biplane cineradiography successfully measured in vivo canine right ventricular volume at 60 Hz, demonstrating RV ejection without significant isovolumic contraction.
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