Key result
Goal-directed hemodynamic therapy may reduce adverse event rates after major orthopedic surgery, though large multicenter trials are required to confirm these findings and eliminate bias.
Why the study?
Does goal-directed hemodynamic therapy reduce adverse event rates in patients undergoing major orthopedic surgery under regional anesthesia?
Population
Patients undergoing major orthopedic surgery (hip replacement) under regional anesthesia
Comparison
Goal-directed hemodynamic therapy using fluid… vs Usual care
Design
Editorial
Authors
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While small trials suggest goal-directed hemodynamic therapy may reduce postoperative adverse events in orthopedic surgery, large multicenter trials are necessary to definitively resolve uncertainty and minimize bias.
Does goal-directed hemodynamic therapy reduce adverse event rates in patients undergoing major orthopedic surgery under regional anesthesia?
While small trials suggest goal-directed hemodynamic therapy may reduce postoperative adverse events in orthopedic surgery, large multicenter trials are necessary to definitively resolve uncertainty and minimize bias.
MacDonald et al. (2011) conducted an editorial in Major orthopedic surgery. Goal-directed hemodynamic therapy (GDT) vs. Usual care was evaluated. Goal-directed hemodynamic therapy may reduce adverse event rates after major orthopedic surgery, though large multicenter trials are required to confirm these findings and eliminate bias.
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