Key result
Echocardiography measurement of left ventricular end-diastolic diameter correlated significantly with atrial natriuretic peptide in hemodialysis patients without cardiac disease, but not in those with cardiac disease.
Why the study?
Does echocardiography measurement of LVDd reliably estimate dry weight in hemodialysis patients with cardiac disease?
Observational (n=115)
Does echocardiography measurement of LVDd reliably estimate dry weight in hemodialysis patients with cardiac disease?
Echocardiographic measurement of LVDd is a beneficial screening tool to determine dry weight and stabilize blood pressure in hemodialysis patients with cardiac disease, for whom ANP levels may be unreliable.
Answers are grounded in this paper and cite their sources.
LVDd-ANP dissociation in cardiac disease warrants caution with ANP-guided dry weight; leaves open LVDd utility pending prospective validation.
PURPOSE: It is hard to decide an accurate value for the so-called dry weight (DW) in hemodialysis patients with cardiac disease. Our objective is to evaluate the efficacy of echocardiography to decide DW. PATIENTS AND METHODS: 115 patients on hemodialysis were divided into 2 groups: the cardiac disease group and non-cardiac disease group. The relationship between atrial natriuretic peptide (ANP) and left ventricular end-diastolic diameter (LVDd) measured by echocardiography was examined. RESULTS: There was a significant positive relationship between ANP and LVDd in the noncardiac disease group, but no significant relationship was noted in the cardiac disease group. The DW was re-evaluated and transferred into more suitable criteria for the patients who often became unconscious with decreased blood pressure during dialysis. When LVDd slightly increased beyond the new criteria of dry weight, unconsciousness was disappeared and blood pressure became stable. CONCLUSIONS: Echocardiography examination is very beneficial for screening to determine DW for the patients with cardiac disease.
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Yoshimura et al. (2003) conducted an observational in Hemodialysis (n=115). Echocardiography (LVDd measurement) vs. Non-cardiac disease group was evaluated on Relationship between atrial natriuretic peptide (ANP) and left ventricular end-diastolic diameter (LVDd). Echocardiography measurement of left ventricular end-diastolic diameter correlated significantly with atrial natriuretic peptide in hemodialysis patients without cardiac disease, but not in those with cardiac disease.
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