Key result
Long interdialytic intervals and morning hemodialysis shifts were associated with significantly elevated predialysis blood pressures (mean BP 147.56/87 mmHg in a.m. vs 144.83/84.64 mmHg in p.m.).
Why the study?
The study sought to investigate predialysis blood pressure measurements at different time points using an established database.
Does the interdialytic interval and hemodialysis shift affect predialysis blood pressure measurements in hemodialysis patients?
Observational (n=37,081)
Does the interdialytic interval and hemodialysis shift affect predialysis blood pressure measurements in hemodialysis patients?
The long interdialytic interval and morning hemodialysis shifts are associated with significantly higher predialysis blood pressure, highlighting the need to account for measurement timing when interpreting BP in these patients.
OBJECTIVE: We used our established database to investigate predialysis blood pressure (BP) measurements at different time points. METHODS: Our study period spanned from 1 January 2019 to 31 December 2019. The different time points included: the long interdialytic interval versus the short interdialytic interval; different hemodialysis shifts. Multiple linear regression was used to explore the association between BP measurements and different time points. RESULTS: A total of 37 081 cases of hemodialysis therapies were included. After a long interdialytic interval, predialysis SBP and DBP were significantly elevated. Predialysis BP was 147.72/86.73 mmHg on Monday and 148.26/86.52 mmHg on Tuesday, respectively. Both predialysis SBP and DBP were higher in the a.m. shift. The mean BP in the a.m. and p.m. shifts were 147.56/87 mmHg and 144.83/84.64 mmHg, respectively. In both diabetic nephropathy and non-diabetic nephropathy patients, higher SBP measurements after a long interdialytic interval were observed; however, in diabetic nephropathy patients, we did not find significant differences in DBP among different dates. In diabetic nephropathy and non-diabetic nephropathy patients, we observed that the effect of different shifts on BP was similar. In Monday, Wednesday and Friday subgroups, the long interdialytic interval was also associated with BP; however, in Tuesday, Thursday and Saturday subgroups, different shifts but not the long interdialytic interval was associated with BP. CONCLUSION: The long interdialytic interval and different hemodialysis shifts have a significant effect on predialysis BP in patients with hemodialysis. When interpreting BP in patients with hemodialysis, different time points is a confounder.
No takes yet. Share an insight, caveat, or question.
Lan et al. (2023) conducted an observational in Hemodialysis (n=37,081). Long interdialytic interval and morning shifts vs. Short interdialytic interval and afternoon shifts was evaluated on Predialysis blood pressure. Long interdialytic intervals and morning hemodialysis shifts were associated with significantly elevated predialysis blood pressures (mean BP 147.56/87 mmHg in a.m. vs 144.83/84.64 mmHg in p.m.).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: