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Concentrations of the polyamines spermidine and spermine and of glutathione have been studied in livers of normal rats and in livers and tumours of rats bearing Rd/3 sarcoma transplants. In livers of tumour‐bearing rats it was found that the spermidine content increased and glutathione content diminished with increasing tumour size.
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Neish et al. (1967) studied this question.
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