Key result
Spontaneous ventricular tachycardia was associated with considerably increased plasma concentrations of atrial natriuretic factor (mean 745 pg/ml), which remained elevated 24 hours after reversion.
Observational (n=15)
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Elevated atrial natriuretic factor during ventricular tachycardia does not appear to significantly contribute to the hypotension often associated with the arrhythmia.
Plasma concentrations of immunoreactive atrial natriuretic factor were considerably increased (mean 745 (376) pg/ml) in 15 patients during spontaneous ventricular tachycardia. There was no significant relation, however, between concentrations of plasma atrial natriuretic factor and systolic arterial blood pressure during tachycardia. Samples taken 30 minutes and 24 hours after reversion of ventricular tachycardia to sinus rhythm showed that, although plasma concentrations of atrial natriuretic factor had fallen significantly, they were still raised after 24 hours. Raised concentrations of atrial natriuretic factor during ventricular tachycardia did not seem to contribute significantly to the hypotension that is often associated with the arrhythmia.
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Twidale et al. (1990) conducted an observational in Spontaneous ventricular tachycardia (n=15). Spontaneous ventricular tachycardia vs. Reversion to sinus rhythm was evaluated on Plasma concentrations of immunoreactive atrial natriuretic factor. Spontaneous ventricular tachycardia was associated with considerably increased plasma concentrations of atrial natriuretic factor (mean 745 pg/ml), which remained elevated 24 hours after reversion.
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