Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
This research is Trending!
September 1, 2026Cardiovascular Diagnosis and TherapyOpen Access

Transcatheter tricuspid repair emerges as a promising surgical alternative for high-risk severe functional TR.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Most patients with severe tricuspid regurgitation are managed medically because isolated tricuspid valve surgery is infrequent, prompting the development of transcatheter therapies for high- and extreme-risk patients.

Design

Review

Key result

Transcatheter tricuspid valve repair therapies are emerging as promising alternatives to surgery in extreme- and high-risk patients with severe functional tricuspid regurgitation.

Authors

Dhaval Kolte
Dhaval KolteInterventional Cardiology
SESammy ElmariahInterventional / Structural Cardiology

Discussion

Loading...

Member takes

Overview

May support transcatheter repair in high-risk functional TR; leaves open optimal timing, selection, and durability for prospective trials.

Key Points

  • To review the current state, safety, and efficacy of transcatheter repair devices for high-risk patients with severe functional tricuspid regurgitation.
  • Reviewed clinical data on transcatheter tricuspid valve repair technologies developed for high- and extreme-risk surgical candidates.
  • Categorized and analyzed devices based on therapeutic mechanism, including direct leaflet coaptation systems and indirect annuloplasty systems.
  • Tricuspid regurgitation affects over 70 million individuals worldwide, with one-year mortality escalating with disease severity, yet isolated surgical repair remains rare.
  • Transcatheter repair techniques targeting leaflet coaptation or annular reduction offer effective, minimally invasive alternatives to standard medical therapy in high-risk patients.
  • Future procedural success relies on refining patient selection criteria, establishing optimal timing for intervention, and verifying long-term device durability.

Structured PICO

P
Population
Extreme- and high-risk patients with severe functional tricuspid regurgitation
I
Intervention
Transcatheter tricuspid valve repair therapies (including leaflet/coaptation devices and annuloplasty devices)

This review summarizes the current state, efficacy, and safety of transcatheter tricuspid valve repair therapies for high-risk patients with severe functional tricuspid regurgitation.

Limitations

  • Appropriate patient selection, optimal timing of intervention, and evaluation of long-term outcomes and device durability remain to be established in ongoing and future studies.
Trending Research#2 this week

ESC 2026 hot line; Medscape coverage; high expert discussion on tricuspid interventions.

Social attention
90
Preprint velocity
60
News coverage
85
Conference
95
Expert commentary
85

Cite This Study

Kolte et al. (2020) conducted a review in Tricuspid Regurgitation. Transcatheter tricuspid valve repair was evaluated. Transcatheter tricuspid valve repair therapies are emerging as promising alternatives to surgery in extreme- and high-risk patients with severe functional tricuspid regurgitation.

synapsesocial.com/papers/6a967f3cef439d566163949chttps://doi.org/10.21037/cdt.2019.09.11
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes2025
  2. 2New Therapeutic Advances in the Management of Tricuspid Valve Regurgitation2024 · 2 citations
  3. 3Transcatheter Tricuspid Valve Replacement: Case Selection, Technical Considerations, and Procedural Planning2023 · 7 citations
  4. 4Developments in transcatheter tricuspid valve therapies2019 · 6 citations
  5. 5A comprehensive overview of surgical and transcatheter therapies to treat tricuspid regurgitation in patients with heart failure2023 · 3 citations