Why the study?
Children undergoing pediatric cardiac surgery with cardiopulmonary bypass experience considerable mortality and morbidity from post-operative bleeding caused primarily by blood clotting impairment, requiring assessment of management tactics.
The management of post-coagulopathy in pediatric cardiac surgery requires a multifaceted approach including targeted use of antifibrinolytics and factor concentrates to reduce bleeding complications.
Management of post-coagulopathy in pediatric cardiac surgery lacks standardized approaches; leaves open the need for rigorous comparative trials.
Background: Children with congenital heart disease undergoing complicated pediatric cardiac surgery with cardiopulmonary bypass (CPB) experience considerable post-operative mortality and morbidity due to post-operative bleeding. An impairment in the blood clotting system primarily contributes to excessive bleeding in children following heart surgery. Aim: to assess the different methods for the treatment of pediatric patients with post-coagulopathy cardiac surgery. Methods: Pubmed, Web of Science, Scopus, Embase, SpringerLink, and the Cochrane Library in order to find various articles concerning this topic were searched. The search strategy; (cardiac surgery) AND (pediatric) AND (coagulopathy) AND (post-operative) was used. The investigation ended in April 2022. Scientific novelty: Post-coagulopathy cardiac surgery is a relatively new medical field that has seen tremendous advances in the past decade. It involves the use of specialised techniques to reduce the risk of bleeding during and after cardiac surgery. This includes the use of anticoagulants, thrombolytics, and other medications to reduce clotting and improve outcomes. In addition, newer technologies such as robotic-assisted surgery have been developed to improve precision and accuracy during cardiac procedures. Therefore, this review aims to address the tactics of managing children-patients with post-coagulopathy cardiac surgery Conclusion: The management of children-patients with post-coagulopathy cardiac surgery is a particularly challenging area due to their unique physiology and anatomy. As such, there is a need for novel approaches to ensure optimal outcomes for these patients. For example, research has shown that using anticoagulants in combination with thrombolytics can reduce the risk of bleeding complications following cardiac surgery in pediatric patients.
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A 2022 study studied this question.
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