Why the study?
Previous studies linked ultrafiltration with improved outcomes and reduced mortality during cardiopulmonary bypass, motivating a pooled analysis of its perioperative association with clinical outcomes in adults.
Does ultrafiltration reduce perioperative bleeding, transfusion requirements, and ICU length of stay in adult patients undergoing cardiopulmonary bypass?
Does ultrafiltration reduce perioperative bleeding, transfusion requirements, and ICU length of stay in adult patients undergoing cardiopulmonary bypass?
In adults undergoing cardiopulmonary bypass, ultrafiltration reduces perioperative bleeding, transfusion requirements, and ICU length of stay, but does not significantly impact major cardiovascular outcomes or mortality.
UF may curb bleeding and transfusion needs in adult CPB; extends prior data but leaves major outcome benefits unproven.
Introduction: Previous studies have shown that ultrafiltration (UF) is associated with improved minor and major outcomes of cardiopulmonary bypass (CPB) by improving tissue perfusion as well as lowering the patient's hematocrit and blood loss and finally reducing the mortality. This meta-analysis aimed to pool the data of the previous studies on the association between using UF in the perioperative period and clinical outcomes in adult patients undergoing CPB.
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Al‐Sadawi et al. (2020) studied this question.
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