Heat resistance in polioviruses is an independent genetic marker from multiplication capacity at 40°C or plating efficiency at low bicarbonate concentrations.
Heat resistance marks polioviruses independently; leaves open its utility for strain differentiation in research.
The genetic marker involving resistance of polioviruses to heating at 50°C is independent of the capacity of mutants to multiply at 40 °C or their plating efficiency at low bicarbonate concentrations. The possible usefulness of heat-resistant mutants for the study of attenuated poliovirus strains is discussed.
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Papaevangelou et al. (1961) studied this question.
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