Why the study?
Does an extended core test panel and DDAVP challenge improve the identification and functional characterization of von Willebrand disease compared to the classic approach?
Population
Individuals with defects or deficiencies in von Willebrand factor (VWF) / von Willebrand disease (VWD)
Comparison
Extended core test panel including collagen… vs Classic approach of classification and…
Design
Review
Authors
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May support extended VWD panels in select cases; leaves open need for prospective validation vs standard testing.
Does an extended core test panel and DDAVP challenge improve the identification and functional characterization of von Willebrand disease compared to the classic approach?
An extended diagnostic panel including collagen binding and DDAVP challenge may improve the challenging classification and functional characterization of von Willebrand disease.
Emmanuel J. Favaloro (2009) studied this question.
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