January 1, 2011Thrombosis and HaemostasisOpen Access

Gynaecological and obstetric bleeding in moderate and severe von Willebrand disease

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Population

423 women aged ≥16 years with moderate and severe von Willebrand disease (VWD) in the Netherlands.

Design

Cross-sectional

Authors

EWEva M. de WeeErasmus MC HKH.M. KnolUniversity Medical Center Groningen JBJohanna G. van der BomLeiden University Medical Center

Discussion

Member takes

Implication

Signals substantial reproductive bleeding morbidity in moderate-severe vWD; leaves open targeted therapeutic trials in prospective cohorts.

Structured PICO

Population

423 women aged ≥16 years with moderate and severe von Willebrand disease (VWD) in the Netherlands.

Outcome

Gynaecological and obstetrical symptoms (including menorrhagia, hysterectomy, bleeding after childbirth or pregnancy loss, and number of live births)patient reported

Women with moderate or severe von Willebrand disease experience high rates of menorrhagia, hysterectomy, and obstetric bleeding complications, though progeny is unaffected.

Cite This Study

Wee et al. (2011) studied this question.

synapsesocial.com/papers/6a968d142af794539aa6bbcf https://doi.org/10.1160/th11-03-0180

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Implication

Signals substantial reproductive bleeding morbidity in moderate-severe vWD; leaves open targeted therapeutic trials in prospective cohorts.

Gynaecological and obstetric bleeding in moderate and severe von Willebrand disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Gynaecological and obstetric bleeding in moderate and severe von Willebrand disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider