Key result
Among women with von Willebrand disease unresponsive to DDAVP, 80% experienced severe menorrhagia requiring blood products, and oral contraceptives were effective for chronic menorrhagia in 88%.
Population
44 women with types of von Willebrand disease (vWd) unresponsive to DDAVP
Design
Cohort
Authors
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Oral contraceptives may aid chronic menorrhagia in DDAVP-unresponsive VWD; leaves open need for prospective trials on severe bleeding management.
Observational (n=44)
Yes
Women with DDAVP-unresponsive von Willebrand disease experience high rates of severe menorrhagia and hysterectomy, though oral contraceptives are effective for managing chronic menorrhagia in most patients.
Paul Foster (1995) conducted an observational in von Willebrand disease unresponsive to DDAVP (n=44). von Willebrand disease unresponsive to DDAVP was evaluated on Severe menorrhagia requiring blood product therapy. Among women with von Willebrand disease unresponsive to DDAVP, 80% experienced severe menorrhagia requiring blood products, and oral contraceptives were effective for chronic menorrhagia in 88%.
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