Why the study?
Does twin gestation increase the incidence of pre-eclampsia/eclampsia compared to singleton pregnancies?
Population
1045 twin gestations
Comparison
Twin pregnancy (and zygosity assessment) vs Singleton pregnancies
Design
Cohort
Authors
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May support intensified monitoring in twin pregnancies; leaves open mechanisms and prevention strategies pending prospective validation.
Does twin gestation increase the incidence of pre-eclampsia/eclampsia compared to singleton pregnancies?
Twin pregnancies are associated with a threefold higher incidence of pre-eclampsia/eclampsia compared to singleton pregnancies, largely independent of zygosity.
McFarlane et al. (1976) studied this question.
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