Why the study?
Does epidural levobupivacaine with or without fentanyl reduce the need for rescue analgesia in children undergoing urologic or abdominal surgery?
Population
120 healthy children aged 6 months to 12 yr scheduled to undergo urologic or abdominal surgery
Comparison
Continuous epidural infusion for 24 h of one of… vs Active comparators
Design
RCT, randomized in a double-blinded and concealed manner, double-blinded
Follow-up
24 h
Authors
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Levobupivacaine alone matches fentanyl combinations for pediatric epidural analgesia; confirms no added benefit from fentanyl and supports opioid-sparing use.
Does epidural levobupivacaine with or without fentanyl reduce the need for rescue analgesia in children undergoing urologic or abdominal surgery?
0.0625% levobupivacaine without fentanyl is an effective and safe perioperative epidural solution in children when infused at a rate of 0.3 ml/kg/h.
Lerman et al. (2003) studied this question.
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