What question did this study set out to answer?

To assess the safety and efficacy of intrathecal hyperbaric levobupivacaine alone versus in combination with fentanyl during elective cesarean sections.

February 5, 2026Journal of Obstetric Anaesthesia and Critical CareOpen Access

Intrathecal Hyperbaric Levobupivacaine Alone versus Hyperbaric Levobupivacaine with Fentanyl in Elective Cesarean Section – A Randomized Study

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To assess the safety and efficacy of intrathecal hyperbaric levobupivacaine alone versus in combination with fentanyl during elective cesarean sections.
Conducted a prospective, randomized, double-blind study on 80 ASA II parturients aged 18–30 years.
Patients assigned to two groups: Group L (levobupivacaine alone) and Group LF (levobupivacaine with fentanyl).
Evaluated sensory and motor block characteristics, postoperative analgesia, hemodynamics, neonatal Apgar scores, and side effects.
Group LF had a significantly faster onset of sensory and motor blockade compared to Group L (P < 0.001).
Prolonged duration of sensory block, motor block, and postoperative analgesia observed in Group LF (P < 0.001).
Time to first rescue analgesia was significantly longer in Group LF (162.92 ± 10.99 minutes) than in Group L (145.2 ± 11.86 minutes) (P < 0.05).
Both groups maintained stable hemodynamics with no major side effects reported.

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Implication

Randomized study evaluates analgesia and safety of levobupivacaine alone and with fentanyl in parturients, suggesting a better option with fentanyl.

Cite This Study

Sumith et al. (2026) studied this question.

synapsesocial.com/papers/69843543f1d9ada3c1fb3d6d https://doi.org/10.4103/joacc.joacc_35_25

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Implication

Randomized study evaluates analgesia and safety of levobupivacaine alone and with fentanyl in parturients, suggesting a better option with fentanyl.

Intrathecal Hyperbaric Levobupivacaine Alone versus Hyperbaric Levobupivacaine with Fentanyl in Elective Cesarean Section – A Randomized Study

Key Points

Discussion

Implication

Cite This Study

Intrathecal Hyperbaric Levobupivacaine Alone versus Hyperbaric Levobupivacaine with Fentanyl in Elective Cesarean Section – A Randomized Study

Key Points

Discussion

Implication

Cite This Study

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