Key result
Acute myocarditis was associated with significantly prolonged Tp-e intervals (85 vs 74 ms, p<0.001) and increased Tp-e/QT and Tp-e/QTc ratios compared to healthy controls.
Why the study?
Myocarditis contributes to unexplained mortality and is a major cause of sudden cardiac death in early life, motivating the assessment of repolarization dispersion on 12-lead surface ECG in acute myocarditis.
Are ventricular repolarization dispersion parameters (Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios) increased in patients with acute myocarditis compared to healthy controls?
Population
56 patients with acute myocarditis and 56 control subjects
Comparison
Patients with acute myocarditis vs control subjects
Follow-up
In hospital follow-up time was 6 ± 2 days
Authors
Loading...
Tp-e parameters may aid arrhythmia risk assessment in acute myocarditis; leaves open whether they predict clinical outcomes.
Case-Control (n=112)
Single-blind
No
Are ventricular repolarization dispersion parameters (Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios) increased in patients with acute myocarditis compared to healthy controls?
Absolute Event Rate: 85% vs 74%
p-value: p=<0.001
Ventricular repolarization parameters (Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios) are significantly elevated in acute myocarditis and correlate with myocardial injury markers, potentially serving as indicators for ventricular arrhythmia risk.
Uçar et al. (2019) conducted a case-control in Acute myocarditis (n=112). Acute myocarditis vs. Healthy controls was evaluated on Tp-e interval (ms) (p=<0.001). Acute myocarditis was associated with significantly prolonged Tp-e intervals (85 vs 74 ms, p<0.001) and increased Tp-e/QT and Tp-e/QTc ratios compared to healthy controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: