Key result
Three antigen detection methods and real-time RT-PCR for detecting bovine viral diarrhea virus had a high correlation rate (96.5%) and similar sensitivity and specificity.
Why the study?
How do five diagnostic methods compare for detecting bovine viral diarrhea virus infection in calves?
Population
258 cattle (224 calves 0-3 months of age, 23 calves >3 to <7 months, and 11 cattle >7 months)
Design
Preclinical
Authors
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May aid BVDV detection in calves; leaves open prospective validation before routine use.
Cross-Sectional (n=258)
How do five diagnostic methods compare for detecting bovine viral diarrhea virus infection in calves?
Three antigen detection methods and real-time RT-PCR showed high correlation (96.5%) and similar diagnostic performance for detecting BVDV in calves.
Hilbe et al. (2007) conducted a cross-sectional in Bovine viral diarrhea virus infection (n=258). Five diagnostic methods (IHC, 2 antigen ELISAs, 1 antibody ELISA, real-time RT-PCR) was evaluated on Correlation rate among 3 antigen detection methods and real-time RT-PCR. Three antigen detection methods and real-time RT-PCR for detecting bovine viral diarrhea virus had a high correlation rate (96.5%) and similar sensitivity and specificity.
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